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A novel reporter system for molecular imaging and high-throughput screening of anticancer drugs

  • In: Posters: Drug Design and Discovery
  • At: Bangkok (Thailand) (2014)
  • Type: Poster
  • Poster code: POS-DDD011
  • By: WANG, Chunxia (Nanfang Hospital, Southern Medical University, Pharmacy, Guangzhou, China)
  • Co-author(s): Xie, Jingping (Institute of Imaging Science, Vanderbilt University, Nashville, United States of America)
    Hou, Lianbing (Nanfang Hospital, Southern Medical University, Guangzhou, China)
    Ma, Yun (Nanfang Hospital, Southern Medical University, Guangzhou, China)
    Virostko, John (Institute of Imaging Science, Vanderbilt University, Nashville, United States of America)
    Gore, John (Institute of Imaging Science, Vanderbilt University, Nashville, United States of America)
  • Abstract:

    Background. Apoptosis is irreversible programmed cell death, characterized by a cellular cascade activation of caspase 3, which subsequently degrades proteins and other components of cells with a motif sequence. Aims. Here we report a novel reporter system to detect apoptosis, growth arrest, and cell death based on controlled and self-amplified..

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Last update 28 September 2023

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