Optimized conditions for high level expression of an anti-her2 single-chain antibody fragment in e. coli

• In: Posters: Biotechnology
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-BIO002
• By: AKBARI, Vajihe (Isfahan University of Medical Sciences, Pharmaciutical biotechnology, Isfahan, Iran)
• Co-author(s): Abedi, Daryoush (Isfahan University of Medical Sciences, Isfahan, Iran)
  Mir Mohammad Sadeghi, Hamid (Isfahan University of Medical Sciences, Isfahan, Iran)
  Jafarian-Dehkordi, Abbas (Isfahan University of Medical Sciences, Isfahan, Iran)
  Chou, Perry (Department of Chemical Engineering, University of Waterloo, Waterloo, Canada)
  
• Abstract:

  Background: Human epidermal growth factor receptor (HER) family plays an important role in most kind of cancers. Due to the importance of HER2 receptor, many antibodies with different binding sites and mechanisms of action are under active development to target this receptor Single-chain antibody fragment (ScFv) against HER2 was previously..

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