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Fragment-based lead discovery: Practical aspects of NMR/SPR-based fragment screening
- In: C3 - New Strategies in Modern Medicinal Chemistry on Sunday, 6 September 2009, 9:00-12:00
- At: Istanbul (Turkey) (2009)
- Type: Presentation
- By: MIURA, Takaaki (Chugai Pharmaceutical Co., Ltd., Kamakura, kanagawa, Japan)
- Abstract:
Fragment-based lead discovery (FBLD) has recently emerged as an alternative drug discovery approach to traditional high throughput screening, and has been rapidly integrated into discovery programs in many pharmaceutical companies. In FBLD, weak but specifically binding small "fragments" with MW of ca. 250, are first identified by screening of a
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Last update 28 September 2023