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In vitro ADME studies

  • In: S3 - Improving bioavailability/bioequivalence on Tuesday, 4 September 2007, 9:00-12:00
  • At: Beijing (China) (2007)
  • Type: Presentation
  • By: YAMASHITA, Shinji (Setsunan University, Osaka, Japan)
  • Abstract:

    Permeability and solubility of drugs are considered to be the most important factors to determine oral drug absorption. Caco-2 cell monolayer system is now widely used in the pharmaceutical industries to screen the membrane permeability of new drug-candidates. Also, their water-solubility is measured in vitro at the early stage of drug


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Last update 28 September 2023

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