Downregulation of mir-133b-5p by rest promotes prostate cancer metastasis to bone by targeting tgf-β

• In: D25 What’s new in industry & science? Part 2 on Thursday, 6 September 2018, 09:20 -09:30
• At: Glasgow (Scotland) (2018)
• Type: Presentation
• By: TANG, Yubo (Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, China)
• Co-author(s): Yubo Tang: Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  Shuai Huang: Department of Orthopaedic Surgery, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
  Dong Ren: Department of Orthopaedic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  Peiheng He: Department of Orthopaedic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  Xiao Chen: Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  
• Abstract:

  Background

  High avidity of bone metastasis is an important characteristic in prostate cancer (PCa). Downexpression of miR-133b-5p has been reported to be involved in the development, progression and recurrence in PCa. However, clinical significance and biological roles of miR-133b-5p in bone metastasis of PCa remains unclear. 

  Methods

  We used

  ..

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