Targeted inhibition of atp-bing cassette transporter a1 protein degradation promotes reverse cholesterol transport and reduces atherosclerosis in mice
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: ZHU, Haibo (Beijing, China)
- Co-author(s): Huang, LinZhang (, Beijing, China)
Fan, BaoYan (, Beijing, China)
ATP-Bing Cassette Transporter A1 (ABCA1) is a key protein in the rate-limiting step of reverse cholesterol transport, which maintains plasma HDL levels. Transcriptional regulating ABCA1 promotes HDL generation and RCT is well established, however, little is known about the posttranspcriptional inhibition of ABCA1 degradation on.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.