Population pharmacokinetics of orally administered mefloquine in healthy volunteers and patients with uncomplicated plasmodium falciparum malaria

• In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PG-038
• By: REUTER, Stephanie (University of South Australia, School of Pharmacy & Medical Sciences, Adelaide, Australia)
• Co-author(s): Upton (University of South Australia, Adelaide, Australia)
  Evans, Allan (University of South Australia, Adelaide, Australia)
  Navaratnam (Universiti Sains Malaysia, Penang, Malaysia)
  Olliaro (World Health Organization, Geneva, Switzerland)
  
• Abstract:

  The determination of dosing regimens for the treatment of malaria is largely empirical and thus a better understanding of the pharmacokinetic/pharmacodynamic properties of anti-malarial agents such as mefloquine is required to assess the adequacy of current treatment regimens and identify sources of sub-optimal dosing which could select for..

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