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  • In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PG-033
  • By: WATANABE, Yoshiteru (Showa Pharmaceutical University, Pharmaceutics and Biopharmaceutics, Tokyo, Japan)
  • Co-author(s): Washiyama, Makiko (Showa Pharmaceutical University, Tokyo, Japan)
    Koizumi, Naoya (Showa Pharmaceutical University, Tokyo, Japan)
    Fujii, Makiko (Showa Pharmaceutical University, Tokyo, Japan)
  • Abstract:

    Background: Numerous attempts have been made to control permeability of macromolecular drugs through paracellular routes. Paracellular permeability across epithelial cell monolayers is principally controlled by tight junction (TJ). Sec61β is the β subunit of the Sec61 translocon and contributes expression and delivery of basolateral membrane..

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Last update 4 October 2019

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