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A new empirical modelling approach for quantifying bacterial killing and regrowth in in vitro static time-kill studies

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: CHEAH, Soon-Ee (Monash Institute of Pharmaceutical Sciences, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
  • Co-author(s): Bulitta, Jurgen (Centre for Medicine Use and Safety, Monash University, Parkville, Australia)
    Li, Jian (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
    Nation, Roger (Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
  • Abstract:

    Background
    In vitro static time-kill (STK) studies are integral to optimal antibiotic dosage regimen design. However, there are few efficient mathematical methods for analysing large numbers of STK datasets.
    Aims
    To develop a new mathematical approach to analyse STK data and compare its performance to two established approaches, area under the..

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Last update 4 October 2019

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