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The impact of intravenous sbe7-

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: LEONG, Nathania (Monash University, Monash Institute of Pharmaceutical Science, Parkville, Australia)
  • Co-author(s): Shackleford, David (Monash University, Parkville, Australia)
    Prankerd, Richard (Monash University, Parkville, Australia)
    Mcintosh, Michelle (Monash University, Parkville, Australia)
  • Abstract:

    Background:
    Indinavir (IND) has limited aqueous solubility, and a high incidence of crystalluria has contributed to decreased clinical use. Highly water soluble cyclodextrins such as sulfobutylether7-β-cyclodextrin (SBE7-β-CD) can form soluble inclusion complexes with IND. As SBE7-β-CD is primarily cleared from the systemic circulation by..

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Last update 4 October 2019

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