The impact of intravenous sbe7-
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: LEONG, Nathania (Monash University, Monash Institute of Pharmaceutical Science, Parkville, Australia)
- Co-author(s): Shackleford, David (Monash University, Parkville, Australia)
Prankerd, Richard (Monash University, Parkville, Australia)
Mcintosh, Michelle (Monash University, Parkville, Australia)
Indinavir (IND) has limited aqueous solubility, and a high incidence of crystalluria has contributed to decreased clinical use. Highly water soluble cyclodextrins such as sulfobutylether7-β-cyclodextrin (SBE7-β-CD) can form soluble inclusion complexes with IND. As SBE7-β-CD is primarily cleared from the systemic circulation by.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.