Abcb1 and abcg2 mediate transport of abacavir and hinder its passage across the placenta
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: STAUD, Frantisek (Charles University, Faculty of Pharmacy, Pharmacology and toxicology, Hradec kralove, Czech Republic)
- Co-author(s): Neumanova, Zuzana (Charles University, Faculty of Pharmacy, Hradec kralove, Czech Republic)
Cerveny, Lukas (Charles University, Faculty of Pharmacy, Hradec kralove, Czech Republic)
I. Background: Abacavir is a nucleoside reverse transcriptase inhibitor that is used in pregnant women to prevent mother-to-child-transmission of HIV infection. Together with other antiretroviral agents, it is administered throughout the whole period of pregnancy; however its transport across the placenta has not been fully elucidated to date.II... The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.