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In vitro intestinal models for predicting herb-drug interactions during oral drug delivery

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • By: TARIRAI, Clemence (Tshwane University of Technology, Pharmaceutical Sciences, Pretoria, South Africa)
  • Abstract:

    Background: Phytochemicals may modulate drug transporters consequently affecting the pharmacokinetics of co-administered drugs.
    Aims: Caco-2 cells and excised pig jejunum tissue were evaluated for predicting herb-transporter-drug interactions. Fruit extracts were assessed as functional excipients incorporation in oral dosage forms.

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Last update 4 October 2019

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