In vitro intestinal models for predicting herb-drug interactions during oral drug delivery
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: TARIRAI, Clemence (Tshwane University of Technology, Pharmaceutical Sciences, Pretoria, South Africa)
Background: Phytochemicals may modulate drug transporters consequently affecting the pharmacokinetics of co-administered drugs.
Aims: Caco-2 cells and excised pig jejunum tissue were evaluated for predicting herb-transporter-drug interactions. Fruit extracts were assessed as functional excipients incorporation in oral dosage forms.
Methods:.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.