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The effect of asetic ethyl fraction of ethanol extract of pasak bumi (eurycoma longifolia jack) on p53 expression in sd mice induced by dmba ((dimetil benzo(a)anthrasen)

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: NURANI, Laela Hayu (Faculty of Pharmacy, University of Ahmad Dahlan Yogyakarta, Pharmacy, Laboratory of Phytochemistry, Yogyakarta, Indonesia)
  • Abstract:

    Background. Breast cancer incidence in Indonesia is increasing. P-450 1B1 cytochrome activates DMBA to create DNA adduct which influences mutation on p-53.
    Aims. This research aims to study the effect of extract on the p-53 expression induced by DMBA.
    Methods. Forty nine mice were divided into 7 groups. Group 1,2,3,4 and 7 were treated with 20..

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Last update 4 October 2019

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