The effect of asetic ethyl fraction of ethanol extract of pasak bumi (eurycoma longifolia jack) on p53 expression in sd mice induced by dmba ((dimetil benzo(a)anthrasen)
- At: PSWC, Melbourne (Australia) (2014)
- Type: Poster
- By: NURANI, Laela Hayu (Faculty of Pharmacy, University of Ahmad Dahlan Yogyakarta, Pharmacy, Laboratory of Phytochemistry, Yogyakarta, Indonesia)
Background. Breast cancer incidence in Indonesia is increasing. P-450 1B1 cytochrome activates DMBA to create DNA adduct which influences mutation on p-53.
Aims. This research aims to study the effect of extract on the p-53 expression induced by DMBA.
Methods. Forty nine mice were divided into 7 groups. Group 1,2,3,4 and 7 were treated with 20.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.