Optimization of spray dried microspheres for pulmonary inhalation development: exploring a new drug delivery route for melatonin
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: ZHAO, Min (UCL School of Pharmacy, Department of Pharmaceutics, London, United Kingdom)
- Co-author(s): Samaro, Aseel (UCL School of Pharmacy, London, United Kingdom)
Orlu Gul, Mine (UCL School of Pharmacy, London, United Kingdom)
Casati, Federica (UCL School of Pharmacy, London, United Kingdom)
Background: Melatonin, a drug for the treatment of insomnia, has a very low oral bioavailability (15%) mainly due to the extensive first pass metabolism in the liver. This leads to great interest in establishing whether pulmonary dry powder inhalation (DPI) is a promising route to deliver melatonin as a means of improving the bioavailability.
Aim: .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.