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Enhancing the dissolution of anti cancer flavonoid naringenin utilizing self nanoemulsifying drug delivery system (snedds) and solid dispersions- a comparative evaluation

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: KHAN, Abdul Wadood (jamia hamdard, New delhi, India)
  • Co-author(s): Kotta, Sabna (jamia hamdard, New delhi, India)
    Ansari, Shahid Husain (jamia hamdard, New delhi, India)
    Sharma, Rakesh Kumar (Division of CBRN Defense, Institute of Nuclear Medicine and Allied Sciences, New delhi, India)
    Ali, Javed (jamia hamdard, New delhi, India)
  • Abstract:

    The flavonoid aglycone Naringenin, present in grapefruits, possesses anti-inflammatory, anti-carcinogenic, hepato-protective and anti-lipid peroxidation effects. The therapeutic applications of Naringenin are limited because of poor solubility in water leading to slow dissolution after oral ingestion. Its bioavailability is only 5.8% in humans..

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Last update 4 October 2019

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