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Biodistribution and biostability evaluations of sirna based on near-infrared florescence imaging analysis

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: OKUDA, Tomoyuki (Meijo University, Faculty of pharmacy, Nagoya, Japan)
  • Co-author(s): Toyoda (Meijo University, Nagoya, Japan)
    Okamoto (Meijo University, Nagoya, Japan)
  • Abstract:

    Background: The labeling of small interfering RNA (siRNA) with near-infrared fluorescence (NIRF) probes has attracted much attention to the noninvasive biodistribution study of siRNA using in vivo imaging technology. However, the fluorescence detected in body does not always correspond to intact siRNA due to the cleavage of NIRF probes or the..

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Last update 4 October 2019

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