Possible mechanisms of high drug permeability obtained from dry powder formulations for inhalation in air-interfaced cell culture system
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: ASAI, Ayumu (Meijo University, Drug Delivery Research, Nagoya, Japan)
- Co-author(s): Okuda, Tomoyuki (Meijo University, Nagoya, Japan)
Yamauchi, Tomoyo (Meijo University, Nagoya, Japan)
Okamoto, Hirokazu (Meijo University, Nagoya, Japan)
Purpose: Air-interfaced cell cuture systems (AIC) have been attractive ones for the close evaluations of local action and permeation of drugs in inhaled fomulations. Using AIC, we found that spray freeze dried powders showed higher drug permeability than the similar solutions. In this study, thus, the mechanisms under higher drug permeability were .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.