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Validated lc-ms/ms method for the determination - o6-methylguanine in cancer patients

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: HARAHAP, Yahdiana (Faculty of Pharmacy, University of Indonesia, Depok, Indonesia)
  • Co-author(s): Andalusia, Rizka (Cancer Dharmais Hospital, Jakarta, Indonesia)
    Harmita, Harmita (Faculty of Pharmacy, University of Indonesia, Depok, Indonesia)
    Nurfaradilla, Shinta Ayu (Faculty of Pharmacy, University of Indonesia, Depok, Indonesia)
    Crystalia, Yesa (Faculty of Pharmacy, University of Indonesia, Depok, Indonesia)
  • Abstract:

    Background : O6-Methylguanine and N7-methylguanine which are isomer, were commonly found at low concentration in cancer patients who had been receiving alkylating agent. Therefore, the selective and sensitive analytical method is needed to analyze them
    Aims : To analyze O6-Methylguanine as biomarker in cancer patients blood during administration..

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Last update 4 October 2019

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