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Effect of alcohol on skin permeation and metabolism of p-hydroxyl benzoic acid methyl ester

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: FUJII, Makiko (Showa Pharm. Univ., Machida, Japan)
  • Co-author(s): Ohara, Reiko (Showa Pharm. Univ., Machida, Japan)
    Matsumi, Azusa (Showa Pharm. Univ., Machida, Japan)
    Ohura, Kayoko (Kmamoto Univ., Kumamoto, Japan)
    Koizumi, Naoya (Showa Pharm. Univ., Machida, Japan)
    Imai, Teruko (Kmamoto Univ., Kumamoto, Japan)
    Watanabe, Yoshiteru (Showa Pharm. Univ., Machida, Japan)
  • Abstract:

    I. Background One of the most important characteristics of drug affects the permeation through skin is partition to the skin. Thus, ester-type prodrugs are the candidate of drug because of their lipophilic characteristics, as well as easy to transform active drug in the skin. Alcohol such as ethanol is often used to improve the solubility of..

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Last update 4 October 2019

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