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Amorpohous solid dispersion of dtx: an approach to improve bioavailability

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: SHAIKH, Mohsin (University of South Australia, Adelaide, Australia)
  • Co-author(s): Pang, Zyu Wenn (International Medical University, Kuala lumpur, Malaysia)
    Tan, Hwei Yuin (International Medical University, Kuala lumpur, Malaysia)
    Lim, Sue May (International Medical University, Kuala lumpur, Malaysia)
    Gorajana, Adinarayana (International Medical University, Kuala lumpur, Malaysia)
    Garg, Sanjay (University of South Australia, Adelaide, Australia)
  • Abstract:

    Docetaxel (DTX) is one of the most widely used anticancer compounds. Chronic use of infusion formulation, hospitalization and hypersensitivity reaction caused by Tween 80 present in the marketed preparation are some of the reasons for exploring an alternative oral formulation for DTX. Also, oral bioavailability in humans is prohibitively low..

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Last update 4 October 2019

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