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The lfcs consortium: rank order correlation of in vitro and in vivo performance identified using in vitro digestion testing

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: POUTON, Colin (Monash University, Monash Institute of Pharmaceutical Sciences, Parkville, Australia)
  • Co-author(s): Williams, Hywel (Monash University, Parkville, Australia)
    Anby, Mette (Monash University, Parkville, Australia)
    Mcevoy, Claire (Monash University, Parkville, Australia)
    Thomas, Nicky (University of Copenhagen, Copenhagen, Denmark)
    Calderone, Marilyn (Sanofi R&D, Montpellier, France)
    Igonin, Annabel (Capsugel, Illkirch, France)
    Vertommen, Jan (Capsugel, Illkirch, France)
    Blundell, Ross (Sanofi R&D, Montpellier, France)
    Benameur, Hassan (Capsugel, Illkirch, France)
    Mullertz, Anette (University of Copenhagen, Copenhagen, Denmark)
    Porter, Chris (Monash University, Parkville, Australia)
  • Abstract:

    I. Background: The LFCS Consortium aims to establish standardized in vitro tests to support rational lipid-based formulation (LBF) development.
    II. Aims: Here we evaluate in beagle dogs the performance of four fenofibrate-containing LBFs that show performance differences in vitro.
    III. Methods: In vitro dispersion performance was assessed in 250..

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Last update 4 October 2019

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