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Development of a floating drug delivery system based on gas formation or sublimation technique

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: HUANBUTTA, Kampanart (Faculty of Pharmacy, Burapha University, Chonburi, Thailand)
  • Co-author(s): Limmatvapirat, Sontaya (Pharmaceutical Technology Department, Faculty of Pharmacy, Silpakorn University, Nakornpathom, Thailand)
    Sungthongjeen, Srisagul (Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand)
    Sriamornsak, Pornsak (Pharmaceutical Technology Department, Faculty of Pharmacy, Silpakorn University, Nakornpathom, Thailand)
  • Abstract:

    The present study concerns the development of the floating drug delivery system which can prolong the gastric residence time and increase the bioavailability of the active drug. The core tablets containing a model drug, hydrochlorothiazide were prepared by wet granulation method. Various levels of ammonium carbonate (AMC) (i.e. 0-50% w/w) were..

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Last update 4 October 2019

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