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Salted polyethylene oxide for modulation of levodopa release from interpolymeric blend matrices

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: NGWULUKA, Ndidi (University of Jos, Pharmaceutics and Pharmaceutical Technology, Jos, Nigeria)
  • Co-author(s): Nep, Elijah (University of Jos, Jos, Nigeria)
    Ochekpe, Nelson (University of Jos, Jos, Nigeria)
    Olorunfemi, Patrick (University of Jos, Jos, Nigeria)
    Odumosu, Patricia (University of Jos, Jos, Nigeria)
  • Abstract:

    Background
    Although duodenal infusions may produce enhance absorption, subsequent bioavailability and constant plasma concentration of levodopa, it is invasive. Oral delivery is convenient and non-invasive. However, erratic plasma concentrations of levodopa are obtained. A formulation with a near zero order release was developed for oral delivery..

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Last update 4 October 2019

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