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Influence of coating materials on the flowability and dissolution of dry coated fine ibuprofen powders

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: QU, Li (Monash university, Pharmaceutics, Parkville, Australia)
  • Co-author(s): Stewart, Peter (Monash university, Parkville, Australia)
    Hapgood, Karen (Department of Chemical Engineering, Monash University, Clayton, Australia)
    Zhou, Qi (Tony) (Faculty of Pharmacy, University of Sydney, Sydney, Australia)
    Morton, David (Monash university, Parkville, Australia)
  • Abstract:

    Objective
    To investigate the effect of dry coating of a fine cohesive ibuprofen powder via mechanofusion with different coating materials on its flowability and dissolution for formulation design of high drug loading oral delivery.
    Methods
    Mechanofusion was applied to dry coat a fine ibuprofen with coating materials of magnesium stearate (MgSt),..

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Last update 4 October 2019

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