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99mtc-trastuzumab: a potential radiopharmaceutical for the evaluation of the over-expression of her2 in tumors.

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: SAVIO, Eduardo (Facultad de Química, Montevideo, Uruguay)
  • Co-author(s): Cabral, Pablo (Facultad de Ciencias, MONTEVIDEO, Uruguay)
    Robles, Ana (Facultad de Ciencias, MONTEVIDEO, Uruguay)
    Piuma, Lourdes (Facultad de Química, MONTEVIDEO, Uruguay)
    Gambini, Juan Pablo (Facultad de Medicina, MONTEVIDEO, Uruguay)
    Balter, Henia (Facultad de Ciencias, MONTEVIDEO, Uruguay)
    Savio, Eduardo (Facultad de Química, MONTEVIDEO, Uruguay)
  • Abstract:

    Trastuzumab (Herceptin®) is a monoclonal antibody produced by recombinant DNA technology that binds specifically to the human epidermal growth factor receptor-2- protein (also known as HER2). A consequence of the amplification of gene HER2 is an increase in the expression of protein HER2 in the surface of the tumour cells, which result in a..

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Last update 4 October 2019

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