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Synthesis of novel polymeric precipitation inhibitors for improved kinetic stabilisation of supersaturated poorly water soluble drug solutions

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: WARREN, Dallas (Monash Institute of Pharmaceutical Science, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
  • Co-author(s): Benameur, Hassan (Capsugel R&D, Strasbourg, France)
    Williams, Hywel (Capsugel R&D, Strasbourg, France)
    Porter, Christopher (Monash Institute of Pharmaceutical Science, Parkville, Australia)
    Pouton, Colin (Monash Institute of Pharmaceutical Science, Parkville, Australia)
  • Abstract:

    I Background
    Polymers can assist with the kinetic stabilisation of supersaturated aqueous dispersions of poorly water soluble drugs. We have previously obtained a principle component analysis (PCA) cluster model for identification of polymers likely to perform as good polymeric precipitation inhibitors.
    II Aims
    Based on this cluster model, we..

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Last update 4 October 2019

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