Rapid expansion of supercritical solutions (ress) as a tool for simultaneous cocrystallization and micronization of poorly soluble drugs: (ii) dissolution performance and solubility enhancement
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: MUELLERS, Katrin (Eberhard Karls University Tuebingen, Pharmaceutical Technology and Biopharmacy, Tuebingen, Germany)
- Co-author(s): Wahl, Martin (Eberhard Karls University Tuebingen, Tuebingen, Germany)
The RESS process is a promising approach for simultaneous cocrystallization and micronization, which may improve the dissolution performance and solubility of poorly soluble drugs.
To study the effect of RESS cocrystallization on the equilibrium solubility of the poorly-soluble drug ibuprofen (IBU) with nicotinamide (NA)
To.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.