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Rapid expansion of supercritical solutions (ress) as a tool for simultaneous cocrystallization and micronization of poorly soluble drugs: (ii) dissolution performance and solubility enhancement

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • By: MUELLERS, Katrin (Eberhard Karls University Tuebingen, Pharmaceutical Technology and Biopharmacy, Tuebingen, Germany)
  • Co-author(s): Wahl, Martin (Eberhard Karls University Tuebingen, Tuebingen, Germany)
  • Abstract:

    I Background
    The RESS process is a promising approach for simultaneous cocrystallization and micronization, which may improve the dissolution performance and solubility of poorly soluble drugs.
    II Aims
    To study the effect of RESS cocrystallization on the equilibrium solubility of the poorly-soluble drug ibuprofen (IBU) with nicotinamide (NA)

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Last update 4 October 2019

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