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Targeted delivery of mycophenolic acid to the lymphatic system using lipid mimetic prodrugs: triglyceride vs phospholipid analogues

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • By: HU, Luojuan (Monash University, Pharmaceutical Sciences, Melbourne, Australia)
  • Co-author(s): Quach, Tim (Monash University, Melbourne, Australia)
    Han, Sifei (Monash University, Melbourne, Australia)
    Trevaskis, Natalie (Monash University, Melbourne, Australia)
    Simpson, Jamie (Monash University, Melbourne, Australia)
    Porter, Christopher (Monash University, Melbourne, Australia)
  • Abstract:

    Enhanced delivery of immunomodulators to the lymphatics provides opportunities to selectively improve the treatment of immune disease, since the active sites of many immunomodulators are located in the lymphatics. Lipidic prodrugs where drug is covalently conjugated to a lipid moiety provide one approach to the promotion of lymphatic..

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Last update 4 October 2019

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