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Identification of 5,6-quinolinedione as a potential reactive metabolite of primaquine

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: CHIU, Francis (Monash University, CDCO, MIPS, Parkville, Australia)
  • Co-author(s): Ryan, Eileen (Monash University, Parkville, Australia)
    Charman, Susan (Monash University, Parkville, Australia)
  • Abstract:

    Background: The mechanism of primaquine-induced toxicities is unknown but is believed to require metabolic activation. Identification of reactive metabolites will help in understanding of the mechanism of primaquine toxicity. Aim: To identify and characterise reactive metabolites of primaquine, and to examine the mechanism of formation and..

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Last update 4 October 2019

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