Identification of 5,6-quinolinedione as a potential reactive metabolite of primaquine
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: CHIU, Francis (Monash University, CDCO, MIPS, Parkville, Australia)
- Co-author(s): Ryan, Eileen (Monash University, Parkville, Australia)
Charman, Susan (Monash University, Parkville, Australia)
Background: The mechanism of primaquine-induced toxicities is unknown but is believed to require metabolic activation. Identification of reactive metabolites will help in understanding of the mechanism of primaquine toxicity. Aim: To identify and characterise reactive metabolites of primaquine, and to examine the mechanism of formation and.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.