Secure and effective gene vector of polyamidoamine dendrimer pharmaceutically modified with anionic polymer
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Poster
- By: KODAMA, Yukinobu (Nagasaki University Hospital, Hospital Pharmacy, Nagasaki, Japan)
- Co-author(s): Yamashita, Yumi (Nagasaki University Hospital, Nagasaki, Japan)
Kitahara, Takashi (Nagasaki University Hospital, Nagasaki, Japan)
Sasaki, Hitoshi (Nagasaki University Hospital, Nagasaki, Japan)
Background: Gene therapy is a promising approach for the treatmentof both acquired and inherited diseases, whichare lacking effective drug treatments.
Aim: The purpose of this study was to develop a new type of gene vector, polyamidoamine (PAMAM) dendriplex pharmaceutically modified, based on electrostatic interactions, by various anionic polymers.
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