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Construction of fluorescent uricase fusion protein for characterization of urate transporters

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Poster
  • By: NAKAMURA, Makiko (Tokyo University of Pharmacy and Life Sciences, Pathophysiology, Tokyo, Japan)
  • Co-author(s): Mitsuishi, Shohei (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
    Yamane, Chika (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
    Ichida, Kimiyoshi (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
  • Abstract:

    I. Background: Serum urate level is strictly regulated by renal urate reabsorption and secretion through the urate transporters. Therefore, urate transporters could be a therapeutic target for hyperuricemia and the rapid evaluation of urate transporter inhibitors is needed to screen novel anti-hyperuricemic drugs.II. Aims: In this study, it was..

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Last update 4 October 2019

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