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Glycopeptide and lipopeptide antibiotics with potent activity against multi-drug resistant bacteria responsible for uti, csssi and cap/np infections

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: COOPER (Australia)
  • Co-author(s): Blaskovich, Mark (University of Queensland, Brisbane, Australia)
    Butler, Mark (University of Queensland, Brisbane, Australia)
    Becker, Bernd (University of Queensland, Brisbane, Australia)
    Cheng, Mu (University of Queensland, Brisbane, Australia)
    Da Silva, Alberto (University of Queensland, Brisbane, Australia)
    Elliot, Alysha (University of Queensland, Brisbane, Australia)
    Gallardo-Godoy, Alejandra (University of Queensland, Brisbane, Australia)
    Hansford, Karl (University of Queensland, Brisbane, Australia)
    Lindahl, Fredrik (University of Queensland, Brisbane, Australia)
    Paterson, David (University of Queensland, Brisbane, Australia)
    Ziora, Zyta (University of Queensland, Brisbane, Australia)
  • Abstract:

    Background: The paucity of drugs for systemic treatment of multi-drug resistant bacterial infections is one of the most pressing health issues currently facing humankind. New approaches to antibiotic discovery are needed.
    Aims & Methods: We designed lipopeptide and glycopeptide derivatives selective for bacterial membranes over mammalian..

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Last update 4 October 2019

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