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Protein surfactant interaction and temperature dependent adsorption: g-scf formulation

  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Presentation
  • By: BREMMELL, Kristen (University of South Australia, School of Pharmacy and Medical Sciences, Adelaide, Australia)
  • Co-author(s): Chang, Patrick (University of South Australia, Adelaide, Australia)
    Kempson, Ivan (University of South Australia, Adelaide, Australia)
    Barnes, Tim (University of South Australia, Adelaide, Australia)
    Prestidge, Clive (University of South Australia, Adelaide, Australia)
  • Abstract:

    Background: Therapeutic proteins require careful formulation to maximize physical stability and retain their native conformation and commonly include the addition of non-ionic surfactants to aid in reducing protein aggregation and adsorption at interfaces.
    Methods: Interaction between the non-ionic surfactant polysorbate 20 and the therapeutic..

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Last update 4 October 2019

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