The serotonin 5-ht3 receptor c and e subunits influence the response to antagonists
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: IRVING, Helen (Monash University, Drug Discovery Biology, Parkville, Australia)
- Co-author(s): Yaakob, Nor (Monash University, Parkville, Australia)
Nguyen, Dan-Thanh (Monash University, Parkville, Australia)
Exintaris, Betty (Monash University, Parkville, Australia)
Background: The serotonin (5-hydroxytryptamine) 5-HT3 receptor is a ligand gated ion channel found both peripherally and centrally and 5-HT3 receptor antagonists are used to treat various conditions such as irritable bowel syndrome (IBS), chemotherapy induced nausea and vomiting (CINV) and depression. The 5-HT3 receptor consists of various.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.