Delivering plasmid dna to hepatocyte nuclei
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: HUANG, Leaf (University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, Divison of Molecular Pharmaceutics, Chapel hill, United States of America)
Liveris an important organ for metabolism and physiological regulation. Manymetabolic and genetic diseases are associated with liver enzyme malfunction.cDNA delivery to the hepatocytes and subsequent expression in the liver hasstrong implications in therapy of these diseases. We have developed ananoparticle system that will: (1) encapsulate.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.