Development of oral drug product based on bcs concept; integrating drug permeability, solubility and dissolution
- In: SYMPOSIUM: CHALLENGES FOR THE DEVELOPMENT OF DRUGS WITH LOW AQUEOUS SOLUBILITY AND/OR LOW PERMEABILITY on Monday, 14 April 2014, 10:30-12:00
- At: PSWC, Melbourne (Australia) (2014)
- Type: Presentation
- By: YAMASHITA, Shinji (Setsunan University, Faculty of Pharmaceutical Sciences, Osaka, Japan)
Oral drug absorption involves various processes that occur in parallel and/or sequential, starting from the disintegration and dissolution of drugs in the gastrointestinal (GI) fluid, transit through the GI tract, permeation of drug molecules across the intestinal membrane and metabolism in the intestine or liver. Rate and amount of drug.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.