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Expression and function of P-glycoprotein in alveolar epithelial cells and its modulation by cigarette smoke extract

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: YUMOTO, Ryoko (Hiroshima University, Graduate School of Biomedical & Health Sciences, Pharmaceutics and Therapeutics, Hiroshima, Japan)
  • Co-author(s): Sasaki, Yoshihiro (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
    Horiuchi, Taishi (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
    Kato, Yuki (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
    Kishimoto, Umi (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
    Nagai, Junya (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
    Takano, Mikihisa (Hiroshima University, Graduate School of Biomedical & Health Sciences, Hiroshima, Japan)
  • Abstract:


    Background



    In the lung, various transporters are known to be expressed. However, the expression and function of P-glycoprotein (P-gp) in alveolar epithelial cells is still unclear. In addition, the lung is the organ directly exposed to cigarette smoke in smokers. However, the information concerning the effect of cigarette smoke on P-gp in
    ..

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Last update 4 October 2019

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