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Evaluation of efficacy and safety in concomitant use of sildenafil and isosorbide mononitrate in patients with pulmonary arterial hypertension secondary to heart failure

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: WU, Shang-En (Tzu Chi General Hospital Taipei Branch, Pharmacy department, New Taipei city, China Taiwan)
  • Co-author(s): Lee, Chien-hsing (Tzu Chi General Hospital Taipei Branch, New Taipei city, China Taiwan)
  • Abstract:

    I. Background

    Sildenafil, one of phosphodiesterase-5 inhibitors, which induces relaxation of vascular smooth muscle, specifically in pulmonary vasculature, is commonly applied in the treatment of erectile dysfunction and pulmonary arterial hypertension. In heart failure patients, nitrate vasodilators alone may not present adequate pulmonary..

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Last update 4 October 2019

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