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Dissolution Enhancement of Gliclazide Using Ultrasound Waves and Stabilizers in Liquid Anti-Solvent Precipitation

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: AL-NIMRY, Suhair (Jordan University of Science and Technology, Pharmaceutical Technology, Irbid, Jordan)
  • Co-author(s): Qandil, Amjad (Jordan University of Science and Technology, Irbid, Jordan)
    Salem, Mutaz (Jordan University of Science and Technology, Irbid, Jordan)
  • Abstract:


    Background:

    Gliclazide, is a drug of choice in long term sulfonylurea therapy for NIDDM. Rapid GIT absorption is required to prevent a sudden increase in blood glucose level after food intake. The absorption rate of gliclazide is slow and variable among subjects due to poor dissolution from the formulation.


    Aim:

    To enhance the dissolution rate of

    ..

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Last update 4 October 2019

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