Dissolution Enhancement of Gliclazide Using Ultrasound Waves and Stabilizers in Liquid Anti-Solvent Precipitation
- At: 2013 FIP Congress in Dublin (Ireland)
- Type: Poster
- By: AL-NIMRY, Suhair (Jordan University of Science and Technology, Pharmaceutical Technology, Irbid, Jordan)
- Co-author(s): Qandil, Amjad (Jordan University of Science and Technology, Irbid, Jordan)
Salem, Mutaz (Jordan University of Science and Technology, Irbid, Jordan)
Gliclazide, is a drug of choice in long term sulfonylurea therapy for NIDDM. Rapid GIT absorption is required to prevent a sudden increase in blood glucose level after food intake. The absorption rate of gliclazide is slow and variable among subjects due to poor dissolution from the formulation.
To enhance the dissolution rate of .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.