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Bitterness prediction of intact and crushed Vesicare® orally disintegrating tablets using taste sensors

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: HARAGUCHI, Tamami (Mukogawa Women's University, Faculty of Pharmaceutical Sciences, Nishinomiya, Japan)
  • Co-author(s): Miyazaki, Airi (Mukogawa Women's University, Nishinomiya, Japan)
    Yoshida, Miyako (Mukogawa Women's University, Nishinomiya, Japan)
    Hazekawa, Mai (Mukogawa Women's University, Nishinomiya, Japan)
    Uchida, Takahiro (Mukogawa Women's University, Nishinomiya, Japan)
  • Abstract:

    I. Background: Vesicare® tablets, whose main component is solifenacin succinate, are known to be extremely bitter. For children, intact tablets are sometimes broken or crushed in order to administer a lower dose. However, the bitterness of the intact tablet may be enhanced by crushing. Recently, Vesicare® orally disintegrating tablets (ODTs),..

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Last update 4 October 2019

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