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Design Design of de novo designed molecules at the Peroxisome Proliferator Activated Receptor

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: SHOEMAKE, Claire (University of Malta, Pharmacy, Msida, Malta)
  • Co-author(s): Portelli, Stephanie (University of Malta, Msida, Malta)
    Azzopardi, Lilian (University of Malta, Msida, Malta)
  • Abstract:


    Background:

    Rosiglitazone withdrawal from the markethas led to a renewed interest in the Peroxisome Proliferator Activated Receptor ã (PPARã) as target for type 2 diabetes therapies, mainly via partial agonism. This may be achieved via selective PPARã modulators such as S-26948.

    Aim:

    To obtain and optimise molecules having a high affinity to PPARã

    ..

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Last update 4 October 2019

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