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The design of novel lead molecules using a bioisosteric approach

  • At: 2013 FIP Congress in Dublin (Ireland)
  • Type: Poster
  • By: AZZOPARDI, Lilian (University of Malta, Msida, Malta)
  • Co-author(s): Schembri, Maria (University of Malta, Msida, Malta)
    Shoemake, Claire (University of Malta, Msida, Malta)
  • Abstract:


    Background:

    The identification of lead molecules which can be developed into drugs with clinical utility is a challenge in contemporary rational drug design. Bioisosteric manipulation and de novo design are often resorted to in this respect. This project implemented bioisosteric modification on a selected small molecule cohort in the context of a
    ..

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Last update 4 October 2019

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