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Development of lc-ms-ms method for simultaneous determination of prostaglandin e1 (pge1) and prostaglandin e1 ethyl ester (pge1-ee) in dog plasma

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
  • Co-author(s): Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Kwak, Mi-Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Rhee, Jong-Dal (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yoo, Bong-Kyu (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Lyoo, Won Seok (School of Textiles, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Balakrishnan, Prabagar (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Bhandari, Krishna Hari (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Newa, Madhuri (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  • Abstract:

    Purpose: To develop and validate liquid chromatography-mass spectrometry-mass spectrometry (LC-MS-MS) method for the simultaneous determination of prostaglandin E1 (PGE1) and prostaglandin E1 ethyl ester (PGE1-EE) in the plasma of beagle dog. Methods: 9-Anthracenecarboxylic acid was used as an internal standard. The plasma samples were..

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Last update 4 October 2019

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