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RP-HPLC method for determination of ofloxacin and its degradation products in tablets

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: ZIVANOVIC, Ljiljana (Faculty of Pharmacy, Belgrade, Yugoslavia)
  • Co-author(s): Zigic, Gordana (Medicines and Medical Devices Agency, BELGRADE, Serbia and Montenegro)
    Zecevic, Mira (Faculty of Pharmacy, Belgrade, BELGRADE, Serbia and Montenegro)
  • Abstract:

    A quantitative RP-HPLC method was developed and validated for determination and assay of ofloxacin(OF) and its degradation products decarboxy ofloxacin (DOF), 9-piperazino ofloxacin (POF), des-methyl ofloxacin (MOF) and ofloxacin-N-oxide (NOF) in tablets. A RP-HPLC method was performed on XTERRA C18 column with hybrid particle technology at 45oC

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Last update 4 October 2019

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