RP-HPLC method for determination of ofloxacin and its degradation products in tablets
- At: 2006 FIP Congress in Salvadore (Brazil)
- Type: Poster
- By: ZIVANOVIC, Ljiljana (Faculty of Pharmacy, Belgrade, Yugoslavia)
- Co-author(s): Zigic, Gordana (Medicines and Medical Devices Agency, BELGRADE, Serbia and Montenegro)
Zecevic, Mira (Faculty of Pharmacy, Belgrade, BELGRADE, Serbia and Montenegro)
A quantitative RP-HPLC method was developed and validated for determination and assay of ofloxacin(OF) and its degradation products decarboxy ofloxacin (DOF), 9-piperazino ofloxacin (POF), des-methyl ofloxacin (MOF) and ofloxacin-N-oxide (NOF) in tablets. A RP-HPLC method was performed on XTERRA C18 column with hybrid particle technology at 45oC.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.