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Pharmacokinetic analysis of serum ephedrine and pseudoephedorine profiles after oral administration of a kampo kakkonto preparation to healthy volunteers

  • At: 2006 FIP Congress in Salvadore (Brazil)
  • Type: Poster
  • By: INOTSUME, Nobuo (Hokkaido Pharmaceutical Univeristy, Division of Pharmacotherapy, Otaru, Japan)
  • Co-author(s): Fukushima, Shoji (Kobegakuin University, KOBE, Japan)
    Hayakawa, Toru (Hokkaido Pharmaceutical Univeristy, OTARU, Japan)
    Kishimoto, Shuichi (Kobegakuin University, KOBE, Japan)
    Yanaguimoto, Hitomi (Hokkaido Pharmaceutical Univeristy, OTARU, Japan)
    Goto, Nobuyoshi (Makita Hospital, SAPPORO, Japan)
    Imai, Sumio (Makita Hospital, SAPPORO, Japan)
  • Abstract:

    The pharmacokinetics of serum ephedrine and pseudoephedrine concentrations as the indexed reference ingredients of Kampo Kakkonto herbal medicine (ge-gen-tang in Chinese) was compared after oral administration of two doses the Kakkonto extract preparation. The mean maximum concentrations of ephedrine and pseudoephedrine after a 3.75 g dose were ..

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Last update 4 October 2019

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