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Computer-aided design, synthesis, and biological evaluation of novel 2-substituted aminomethylenepyrimidine-2,4,6-Triones as H1 antihistaminic agents (part2)

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: ELBAYAA, Rasha (Faculty of Pharmacy, Pharmaceutical chemistry, Alexandria, Egypt)
  • Abstract:

    As a part of a research project pertaining to the synthesis of novel candidates as nonsedating, nonclassic H
    1

    histaminergic (H
    1

    ) blockers with low toxicity profiles, some new 2-substituted aminomethylenepyrimidine-2,4,6-triones were designed based on the H
    1

    histaminic receptor pharmacophore model. The interactions between the designed compounds

    ..

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Last update 4 October 2019

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