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Percolation behavior in paracellular permeability

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: WASHIYAMA, Makiko (Showa Pharmaceutical University, Pharmaceutical, Tokyo, Japan)
  • Co-author(s): Koizumi, N. (Showa Pharmaceutical University, Tokyo, Japan)
    Fujii, M. (Showa Pharmaceutical University, Tokyo, Japan)
    Kondoh, M. (Graduate school of Pharmaceutical Sciences, Osaka University, Osaka, Japan)
    Yagi, K. (Graduate school of Pharmaceutical Sciences, Osaka University, Osaka, Japan)
    Watanabe, Y. (Showa Pharmaceutical University, Tokyo, Japan)
  • Abstract:

    Background
    Paracellular pathway is an important route especially for macromolecular drug delivery. The paracellular permeability is controlled by tight junctions (TJ), which located at the most apical side of cell-cell contacts. Claudins are major constituents of TJ and form strand network at the TJ. Sodium caprate (C10) and C-terminus fragment of
    C

    ..

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Last update 4 October 2019

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