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In vitro-in vivo correlations for an amorphous formulation of a poorly soluble compound

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: FOTAKI, Nikoletta (University of Bath, Pharmacy and Pharmacology, Bath, United Kingdom)
  • Co-author(s): Long, C.M. (University of Bath, Bath, United Kingdom)
    Tang, K. (Pharmaceutical and Analytical R&D, Hoffmann-La Roche, Nutley, United States of America)
    Chokshi, H. (Pharmaceutical and Analytical R&D, Hoffmann-La Roche, Nutley, United States of America)
  • Abstract:


    Background: 

    Dissolution testing can play an important role as an in vitro surrogate for in vivo performance that can guide formulation development and ascertain the need for bioequivalence tests. Selection of the appropriate  in vitro conditions (media and hydrodynamics) that simulate the in vivo conditions can lead to the generation of successful 

    ..

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Last update 4 October 2019

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