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Antioxidant flavonoids from Rhamnaceous plants Cu(II)-induced cell death by reducing reactive oxygen species in human Hep G2 cancer cells and normal mouse liver cells

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: YANG, Shyh-Chyun (Kaohsiung Medical University, School of Pharmacy, Kaohsiung, China Taiwan)
  • Co-author(s): Lin, K.-W. (Kaohsiung Medical University, Kaohsiung, China Taiwan)
    Ko, H.-H. (Kaohsiung Medical University, Kaohsiung, China Taiwan)
    Hsu, H.-Y. (Tzu-Chi University, Hualien, China Taiwan)
    Lin, C.-N. (Kaohsiung Medical University, Kaohsiung, China Taiwan)
  • Abstract:

    Four structurally related flavonoids
    1

    -
    4

    isolated from Rhamnaceous plants significantly showed 1,1-diphenyl-2-picrylhydrazyl (DPPH
    ?

    )
    -

    scavenging activity and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical cation scavenging activity while compounds
    1

    -
    3

    displayed inhibitory effect on xanthine oxidase (XO). Selective
    1

    ..

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Last update 4 October 2019

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