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Development and evaluation of SPG membrane emulsification system for enhanced oral bioavailability of itraconazole

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, College of Pharmacy, Gyeongsangbuk-do, South-Korea)
  • Co-author(s): Lee, D.W. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Cho, H.J. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Kim, J.H. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Hiep, T.T. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Poudel, B.K. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Ramasamy, T.G. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Yoo, B.K. (College of Pharmacy, Gachon University, South-Korea)
    Kim, J.O. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
    Marasini, N. (Yeungnam University, Gyeongsangbuk-do, South-Korea)
  • Abstract:






    Background:

    Itraconazole, a triazole antifungal drug has low aqueous solubility and bioavailability. Lots of studies have been done to increase solubility of drug with emulsification technique. The emulsion prepared by Shirasu-porous-glass (SPG) membrane can be mono-dispersed and uniform sized emulsion with narrow size distribution.
    Aims:

    The

    ..

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Last update 4 October 2019

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